Compile Data Set for Download or QSAR
maximum 50k data
Found 33 of ic50 data for polymerid = 2442,5269,50000644,50000871,50003915
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50612694(CHEMBL5281742)
Affinity DataIC50:  0.885nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50506040(CHEMBL4536502)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [3H] 3-MC from AhR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Danio rerio)
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50525571(CHEMBL4467659)
Affinity DataIC50:  3.40nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Danio rerio)
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50525574(CHEMBL4546269)
Affinity DataIC50:  8.30nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Danio rerio)
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50525570(CHEMBL4463944)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Danio rerio)
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50525573(CHEMBL4470684)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50439845(CHEMBL2420083)
Affinity DataIC50:  21nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR incubated for 20 mins by gamma counting based autoradiograph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Rattus norvegicus)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50240990(2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole | 5-...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]tetrachlorodibenzo-p-dioxin from aryl hydrocarbon receptor in CRL:WI rat liver cytosolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Mus musculus (Mouse))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50014323(2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE | 2-Phenyl-benzo...)
Affinity DataIC50:  25nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR incubated for 20 mins by gamma counting based autoradiograph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50240990(2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole | 5-...)
Affinity DataIC50:  25nMAssay Description:Binding affinity to AhR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of aryl hydrocarbon receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50525572(CH-223191 | CHEMBL1743245)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at AhR (unknown origin) assessed as inhibition of TCDD-induced luciferase activityMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50612692(CHEMBL5266911)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at AhR (unknown origin) expressed in human U87 cells assessed as inhibition of kynurenic acid-induced transactivation by Renilla/...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50612695(CHEMBL5271453)
Affinity DataIC50:  82nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Danio rerio)
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50525572(CH-223191 | CHEMBL1743245)
Affinity DataIC50:  98nMAssay Description:Antagonist activity at zebrafish AhR2 expressed in COS7 cells transfected with ARNT-1c, Cyp1a-firefly luciferase and pRL-TK Renilla luciferase plasmi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50612699(CHEMBL4303221)
Affinity DataIC50:  127nMAssay Description:Antagonist activity at AhR in human HepG2 cells assessed as inhibition of TCDD-induced receptor activation pretreated for 1 hr followed by TCDD addit...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50612696(CHEMBL5280174)
Affinity DataIC50: <500nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Rattus norvegicus)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50612693(CHEMBL5267451)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at AhR in rat liver cytosol assessed as inhibition of TCDD-induced AhR/DNA complex formation by gel retardation assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50269353(CHEMBL4105559)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at human AhR expressed in Saccharomyces cerevisiae W303-1A (ATCC 208352) transformed with an episomal plasmid containing a minima...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50525572(CH-223191 | CHEMBL1743245)
Affinity DataIC50:  2.43E+3nMAssay Description:Antagonist activity at AhR in human HepG2 cells assessed as inhibition of FICZ-induced AhR transcriptional activity incubated for 24 hrs by Quanti-Lu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Rattus norvegicus)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50612693(CHEMBL5267451)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of TCDD binding to rat liver cytosol AhRMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50191420((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50:  5.20E+3nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50191436((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-piperazin-1-yl...)
Affinity DataIC50:  5.40E+3nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50269354(CHEMBL1335197)
Affinity DataIC50:  7.60E+3nMAssay Description:Antagonist activity at human AhR expressed in Saccharomyces cerevisiae W303-1A (ATCC 208352) transformed with an episomal plasmid containing a minima...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50612697(CHEMBL3252119)
Affinity DataIC50:  1.10E+4nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50612698(CHEMBL5287208)
Affinity DataIC50:  1.20E+4nMAssay Description:Antagonist activity at AhR (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50191401((2'Z,3' E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrr...)
Affinity DataIC50:  1.30E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50191395((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-pyrro...)
Affinity DataIC50:  1.88E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50191405((2'Z,3'E)-7-bromoindirubin-3'-oxime | CHEMBL373834)
Affinity DataIC50:  2.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50191422((2'Z,3'E)-1-methyl-7-bromoindirubin-3'-[O-(2-dimet...)
Affinity DataIC50:  2.40E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50191396((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50:  2.50E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50191411((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-dimethylaminoe...)
Affinity DataIC50: >3.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAryl hydrocarbon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50191415((2'Z,3'E)-7-bromoindirubin-3'-[O-(2-pyrrolidin-1-y...)
Affinity DataIC50: >3.00E+4nMAssay Description:Survival of mouse AhR +/+ 5L cells after 48 hrs by MTS reduction assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed